301853-84-9
Chemical Structure
Hair cell targeting‐peptide A665
- CAS No.: 301853-84-9
- Formula:C54H93N17O21S
- Molecular Weight:1348.48
SMILES: O=C(N[C@@H](CO)C(N[C@@H]([C@H](O)C)C(N[C@@H](CC1=CNC=N1)C(N[C@@H]([C@H](O)C)C(N[C@@H]([C@H](O)C)C(N[C@@H](CCC(O)=O)C(N[C@@H](CO)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CO)C(N[C@@H](CCSC)C(N[C@@H](C(C)C)C(O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)[C@H](CC(C)C)N
Biological Activity: Hair cell targeting-peptide A665 is a hair cell targeting-peptide that specifically binds to the prestin protein on the surface of inner ear hair cells. Hair cell targeting-peptide A665 can be modified on the surface of nanocarriers and work in synergy with cell-penetrating peptides to enhance the permeability of the cylindrical window membrane, helping loaded drugs cross the blood-labyrinth barrier and enter the inner ear[1].
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Hair cell targeting‐peptide A665 | Hair cell targeting-peptide A665 is a hair cell targeting-peptide that specifically binds to the prestin protein on the surface of inner ear hair cells. Hair cell targeting-peptide A665 can be modified on the surface of nanocarriers and work in synergy with cell-penetrating peptides to enhance the permeability of the cylindrical window membrane, helping loaded drugs cross the blood-labyrinth barrier and enter the inner ear. | |||||||||||||||||||||
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