3019971-97-9
3019971-97-9
Chemical Structure
EGFR-IN-109
- CAS No.: 3019971-97-9
- Formula:C12H16N4OS
- Molecular Weight:264.35
InChIKey: BTDORBMZFOWMQU-UHFFFAOYSA-N
SMILES: NNCC(NC1=O)=NC2=C1C3=C(S2)CC(C)CC3
Biological Activity: EGFR-IN-109 (compound 4) is an EGFR inhibitor, with the IC50 values of 25.8 and 182.3 nM for EGFRWT and EGFRT790M, respectively. EGFR-IN-109 arrests the cancer cells’ growth at the G2/M phase and induces both early and late apoptosis. EGFR-IN-109 can be used in cancer research[1].
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EGFR-IN-109 | EGFR-IN-109 (compound 4) is an EGFR inhibitor, with the IC50 values of 25.8 and 182.3 nM for EGFRWT and EGFRT790M, respectively. EGFR-IN-109 arrests the cancer cells’ growth at the G2/M phase and induces both early and late apoptosis. EGFR-IN-109 can be used in cancer research. | |||||||||||||||||||||
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References
Keywords
