3024090-08-9
3024090-08-9
Chemical Structure
FGFR-IN-9
- CAS No.: 3024090-08-9
- Formula:C25H28N6O3S
- Molecular Weight:492.59
IUPAC Name: N-(4-((3S,5R)-3,5-dimethylpiperazin-1-yl)phenyl)-7-((3-methoxyphenyl)sulfonyl)-7H-pyrrolo[2,3-d]pyrimidin-2-amine
InChIKey: GLRBJDQXLPBXND-HDICACEKSA-N
SMILES: O=S(N1C=CC2=CN=C(NC3=CC=C(N4C[C@H](C)N[C@H](C)C4)C=C3)N=C21)(C5=CC=CC(OC)=C5)=O
Biological Activity: FGFR-IN-9 (Compound 19) is a potent, reversible and orally active FGFR inhibitor with an IC50 of 17.1, 29.6, 30.7, 46.7 and 64.3 nM against FGFR4WT, FGFR3, FGFR4V550L, FGFR2 and FGFR1, respectively[1].
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FGFR-IN-9 | FGFR-IN-9 (Compound 19) is a potent, reversible and orally active FGFR inhibitor with an IC50 of 17.1, 29.6, 30.7, 46.7 and 64.3 nM against FGFR4WT, FGFR3, FGFR4V550L, FGFR2 and FGFR1, respectively. | |||||||||||||||||||||
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References
Keywords
