3025538-34-2
3025538-34-2
Chemical Structure
RNase L ligand 2
- CAS No.: 3025538-34-2
- Formula:C24H24N4O6S
- Molecular Weight:496.54
InChIKey: QFDBQJWRRSHQRL-HKWRFOASSA-N
SMILES: O=C(C(C/1=O)=C(NC2=CC=CC=C2)SC1=C/C3=CC=C(OCCOCCN=[N+]=[N-])C(O)=C3)OCC
Biological Activity: RNase L ligand 2 (compound 6) is the Rnase L ligand part of RNAse L RIBOTAC (HY-168455), an RNA-degrading chimera which binds to a four-way RNA helix called SL5 in the 5’ UTR of the SARS-CoV-2 RNA genome and inhibits the virus replication in lung epithelial carcinoma cells. RNase L ligand 2 can be used in the synthesis of RIBOTAC[1].
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RNase L ligand 2 | RNase L ligand 2 (compound 6) is the Rnase L ligand part of RNAse L RIBOTAC (HY-168455), an RNA-degrading chimera which binds to a four-way RNA helix called SL5 in the 5’ UTR of the SARS-CoV-2 RNA genome and inhibits the virus replication in lung epithelial carcinoma cells. RNase L ligand 2 can be used in the synthesis of RIBOTAC. | |||||||||||||||||||||
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References
Keywords
