302918-83-8
Chemical Structure
5'-O-(4,4'-Dimethoxytrityl)-2'-O-methyl-2-thiouridine
- CAS No.: 302918-83-8
- Formula:C31H32N2O7S
- Molecular Weight:576.66
IUPAC Name: 1-((2R,3R,4R,5R)-5-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-hydroxy-3-methoxytetrahydrofuran-2-yl)-2-thioxo-2,3-dihydropyrimidin-4(1H)-one
InChIKey: KWAXQCAGJXIZKB-YXINZVNLSA-N
SMILES: O[C@H]1[C@@H](OC)[C@H](N2C(NC(C=C2)=O)=S)O[C@@H]1COC(C3=CC=CC=C3)(C4=CC=C(OC)C=C4)C5=CC=C(OC)C=C5
Biological Activity: 5'-O-(4,4'-Dimethoxytrityl)-2'-O-methyl-2-thiouridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
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5'-O-(4,4'-Dimethoxytrityl)-2'-O-methyl-2-thiouridine | 5'-O-(4,4'-Dimethoxytrityl)-2'-O-methyl-2-thiouridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc. | |||||||||||||||||||||
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