302964-08-5
Chemical Structure
Dasatinib intermediate-1
- CAS No.: 302964-08-5
- Formula:C16H13Cl2N5OS
- Molecular Weight:394.28
IUPAC Name: 2-((6-chloro-2-methylpyrimidin-4-yl)amino)-N-(2-chloro-6-methylphenyl)thiazole-5-carboxamide
InChIKey: LMXUWARKUIELGT-UHFFFAOYSA-N
SMILES: O=C(C1=CN=C(NC2=NC(C)=NC(Cl)=C2)S1)NC3=C(C)C=CC=C3Cl
Biological Activity: Dasatinib intermediate-1 is an intermediate in the synthesis of Dasatinib (HY-10181). Dasatinib Is a highly potent, ATP competitive, orally active dual Src/Bcr-Abl inhibitor with potent antitumor activity[1].
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Dasatinib intermediate-1 | 97.0% | Dasatinib intermediate-1 is an intermediate in the synthesis of Dasatinib (HY-10181). Dasatinib Is a highly potent, ATP competitive, orally active dual Src/Bcr-Abl inhibitor with potent antitumor activity. | ||||||||||||||||||||
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Keywords