Dasatinib intermediate-1
Based on 1 Customer Validation
Dasatinib intermediate-1 is an intermediate in the synthesis of Dasatinib (HY-10181). Dasatinib Is a highly potent, ATP competitive, orally active dual Src/Bcr-Abl inhibitor with potent antitumor activity.
For research use only. We do not sell to patients.
- Purity: 97.0%
- CAS No.: 302964-08-5
- Formula: C16H13Cl2N5OS
- Molecular Weight:394.28
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Storage:
-20°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| K562 | GI50 |
0.046 μM
Compound: 3a
|
Growth inhibition of human K562 cells measured after 48 hrs by alamarblue assay
Growth inhibition of human K562 cells measured after 48 hrs by alamarblue assay
|
[PMID: 35944901] |
Chemical Information
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CAS No. 302964-08-5
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Appearance Solid
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Molecular Weight 394.28
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Formula C16H13Cl2N5OS
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Color Off-white to light yellow
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SMILES
O=C(C1=CN=C(NC2=NC(C)=NC(Cl)=C2)S1)NC3=C(C)C=CC=C3Cl
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
-20°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Purity & Documentation
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Data Sheet (268 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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