3030492-72-6
3030492-72-6
Chemical Structure
Ferroptosis-IN-27
- CAS No.: 3030492-72-6
- Formula:C14H8BrNO3Se
- Molecular Weight:397.08
InChIKey: OHRYWIOTIXARNE-UHFFFAOYSA-N
SMILES: O=C(O)C1=CC=CC(N2[Se]C3=C(Br)C=CC=C3C2=O)=C1
Biological Activity: Ferroptosis-IN-27 is a glutathione peroxidase (GPx) mimetic. Ferroptosis-IN-27 inhibits oxidative stress, reduces intracellular ROS levels, decreases lipid peroxidation and alleviates ferrous ion overload, thereby inhibiting ferroptosis and protecting cardiomyocytes from Doxorubicin (HY-15142A)-induced injury. Ferroptosis-IN-27 can be used in studies related to Doxorubicin-induced cardiotoxicity[1].
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Ferroptosis-IN-27 | Ferroptosis-IN-27 is a glutathione peroxidase (GPx) mimetic. Ferroptosis-IN-27 inhibits oxidative stress, reduces intracellular ROS levels, decreases lipid peroxidation and alleviates ferrous ion overload, thereby inhibiting ferroptosis and protecting cardiomyocytes from Doxorubicin (HY-15142A)-induced injury. Ferroptosis-IN-27 can be used in studies related to Doxorubicin-induced cardiotoxicity. | |||||||||||||||||||||
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