3031462-75-3
Chemical Structure
Pks13-TE inhibitor 2
- CAS No.: 3031462-75-3
- Formula:C22H19NO5
- Molecular Weight:377.39
IUPAC Name: 2-cyclopentyl-10-hydroxy-2,3-dihydro-1H,13H-chromeno[4',3':2,3]benzofuro[4,5-e][1,3]oxazin-13-one
InChIKey: QCLAVDQVXLANOP-UHFFFAOYSA-N
SMILES: O=C(C1=C2OC3=CC=C(OCN(C4CCCC4)C5)C5=C31)OC6=C2C=CC(O)=C6
Biological Activity: Pks13-TE inhibitor 2 (compound 32) is a 13-Thioesterase (Pks13-TE) inhibitor (IC50=1.30 μM). Pks13-TE inhibitor 2 shows good anti-tuberculosis activity against both agent-sensitive and drug-resistant Mtb strains (MIC=0.0039-0.0078 μg/mL). Pks13-TE inhibitor 2 can be used in studies of multidrug-resistant TB and extensively drug-resistant TB[1].
| Cat. No. | 상품명 | Purity | 제품 설명 | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
Pks13-TE inhibitor 2 | Pks13-TE inhibitor 2 (compound 32) is a 13-Thioesterase (Pks13-TE) inhibitor (IC50=1.30 μM). Pks13-TE inhibitor 2 shows good anti-tuberculosis activity against both agent-sensitive and drug-resistant Mtb strains (MIC=0.0039-0.0078 μg/mL). Pks13-TE inhibitor 2 can be used in studies of multidrug-resistant TB and extensively drug-resistant TB. | |||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
