3033040-76-2
3033040-76-2
Chemical Structure
hCAIX/XII-IN-1
- CAS No.: 3033040-76-2
- Formula:C19H11NO5S2
- Molecular Weight:397.42
IUPAC Name: (Z)-3-(2-oxo-2-(2-oxo-2H-chromen-3-yl)ethyl)-5-(thiophen-2-ylmethylene)thiazolidine-2,4-dione
InChIKey: SUDHZNHUHNIFIK-SXGWCWSVSA-N
SMILES: O=C(C1=CC2=C(OC1=O)C=CC=C2)CN3C(S/C(C3=O)=C\C4=CC=CS4)=O
Biological Activity: hCAIX/XII-IN-1 is a potent CAIX/XII inhibitor with the KI values of 0.48 µM and 0.83 µM for CAIX and CAXII, respectively. hCAIX/XII-IN-1 shows antiproliferative activity in vitro. hCAIX/XII-IN-1 induces apoptosis in MCF-7 cells[1].
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hCAIX/XII-IN-1 | hCAIX/XII-IN-1 is a potent CAIX/XII inhibitor with the KI values of 0.48 µM and 0.83 µM for CAIX and CAXII, respectively. hCAIX/XII-IN-1 shows antiproliferative activity in vitro. hCAIX/XII-IN-1 induces apoptosis in MCF-7 cells. | |||||||||||||||||||||
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