3033865-16-3
Chemical Structure
N,N-Dimethyl-idarubicin
- CAS No.: 3033865-16-3
- Formula:C28H31NO9
- Molecular Weight:525.55
InChIKey: PMSDVJCTKMPXOJ-MKUQNYOISA-N
SMILES: OC1=C2C(C(C3=CC=CC=C3C2=O)=O)=C(O)C([C@H]4O[C@H]5C[C@@H]([C@@H]([C@@H](O5)C)O)N(C)C)=C1C[C@](O)(C4)C(C)=O
Biological Activity: N,N-Dimethyl-idarubicin, an Idarubicin (HY-17381) derivative, is a potent histone evictor which does not induce DNA double-strand breaks. N,N-Dimethyl-idarubicin, an anthracycline, is an effective cytotoxic agent for ABCB1-overexpressing, Doxorubicin-resistant cells[1].
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N,N-Dimethyl-idarubicin | N,N-Dimethyl-idarubicin, an Idarubicin (HY-17381) derivative, is a potent histone evictor which does not induce DNA double-strand breaks. N,N-Dimethyl-idarubicin, an anthracycline, is an effective cytotoxic agent for ABCB1-overexpressing, Doxorubicin-resistant cells. | |||||||||||||||||||||
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Keywords