3034082-58-8
3034082-58-8
Chemical Structure
CDK7-IN-28
- CAS No.: 3034082-58-8
- Formula:C23H27F3N6O
- Molecular Weight:460.50
InChIKey: MEHRTPAPZVPMJI-ZDUSSCGKSA-N
SMILES: FC(F)(C1=CN=C(N=C1C2=CNC3=C2CCCN(C3=O)C4CC4)N[C@@H]5CNC6(CC5)CC6)F
Biological Activity: CDK7-IN-28 (CDK7-1276) is a potent CDK7 inhibitor(IC50＜5 nM). CDK7-IN-28 can inhibit proliferation of MDA-MB-468 cell line by blocking cell cycle and inhibiting DNA replication[1].
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CDK7-IN-28 | CDK7-IN-28 (CDK7-1276) is a potent CDK7 inhibitor(IC50＜5 nM). CDK7-IN-28 can inhibit proliferation of MDA-MB-468 cell line by blocking cell cycle and inhibiting DNA replication. | |||||||||||||||||||||
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