3038330-83-2
Chemical Structure
Surbinsertib
Synonym(s): SGR-3515
- CAS No.: 3038330-83-2
- Formula:C30H40N8O2S
- Molecular Weight:576.76
InChIKey: SZRUXMHQEFKMJJ-AYWVHJORSA-N
SMILES: C[C@]12[C@](CC(C)(OC2)C)([H])N(C3=CC=CC(N=S(C)(C)=O)=N3)C4=NC(NC5=CC=C(N6CCN(CC6)C)C=C5)=NC=C41
Biological Activity: Surbinsertib (SGR-3515) is an orally active dual inhibitor of the Wee1 and Myt1 kinases. Surbinsertib is used in cancer research[1][2].
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Surbinsertib | Surbinsertib (SGR-3515) is an orally active dual inhibitor of the Wee1 and Myt1 kinases. Surbinsertib is used in cancer research. | |||||||||||||||||||||
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References
- [1]. WHO Drug Information, Vol. 40, No. 2, 2026
- [2]. Shaoxian Sun, et al, Abstract 3025: Optimization of therapeutic index of SGR-3515, a first-in-class Wee1/Myt1 inhibitor through intermittent dosing for monotherapy and combination with chemotherapy in xenograft tumor models. Cancer Res 15 April 2025; 85.