3040025-57-5
3040025-57-5
Chemical Structure
RIP1 kinase inhibitor 9
- CAS No.: 3040025-57-5
- Formula:C25H21N3O3
- Molecular Weight:411.45
InChIKey: YXUKPOXQACMKOS-NRFANRHFSA-N
SMILES: CN1C([C@H](COC2=CC=CC=C21)NC(C3=CC4=C(NC=C4C5=CC=CC=C5)C=C3)=O)=O
Biological Activity: RIP1 kinase inhibitor 9 (compound SY-1) is a selective RIP kinase inhibitor. RIP1 kinase inhibitor 9 effectively suppresses the central inflammatory response induced by epilepsy. RIP1 kinase inhibitor 9 inhibits Z-VAD-FMK (HY-16658B)-induced necroptosis in HT-29 cells with an EC50 of 7.04 nM[1].
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RIP1 kinase inhibitor 9 | RIP1 kinase inhibitor 9 (compound SY-1) is a selective RIP kinase inhibitor. RIP1 kinase inhibitor 9 effectively suppresses the central inflammatory response induced by epilepsy. RIP1 kinase inhibitor 9 inhibits Z-VAD-FMK (HY-16658B)-induced necroptosis in HT-29 cells with an EC50 of 7.04 nM. | |||||||||||||||||||||
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