30408-30-1
30408-30-1
Chemical Structure
Nybomycin
- CAS No.: 30408-30-1
- Formula:C16H14N2O4
- Molecular Weight:298.29
IUPAC Name: 8-(hydroxymethyl)-6,11-dimethyl-11-hydro-2H,4H-oxazolo[5,4,3-ij]pyrido[3,2-g]quinoline-4,10-dione
InChIKey: HKMUGCUFXWTNSP-UHFFFAOYSA-N
SMILES: O=C1N2C3=C(C4=C(C=C3C(C)=C1)C(CO)=CC(N4C)=O)OC2
Biological Activity: Nybomycin, an antibiotic, exhibits antiphage and antibacterial properties. Nybomycin binds to DNA and induces a unique morphological change to mycobacterial bacilli leading the bacterial cell death[1][2].
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Nybomycin | Nybomycin, an antibiotic, exhibits antiphage and antibacterial properties. Nybomycin binds to DNA and induces a unique morphological change to mycobacterial bacilli leading the bacterial cell death. | |||||||||||||||||||||
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References
- [1]. Strelitz F, et, al. NYBOMYCIN, A NEW ANTIBIOTIC WITH ANTIPHAGE AND ANTIBACTERIAL PROPERTIES. Proc Natl Acad Sci U S A. 1955 Sep 15;41(9):620-4. [Content Brief]
- [2]. Arai M, et, al. Anti-dormant mycobacterial activity and target analysis of nybomycin produced by a marine-derived Streptomyces sp. Bioorg Med Chem. 2015 Jul 1;23(13):3534-41. [Content Brief]
Keywords
