3047757-68-3
3047757-68-3
Chemical Structure
hCAXII-IN-10
- CAS No.: 3047757-68-3
- Formula:C20H19N7O3S
- Molecular Weight:437.47
InChIKey: QRVORXCXOFUSAR-UHFFFAOYSA-N
SMILES: O=C(C1=NN(C2=CC=C(S(=O)(N)=O)C=C2)C(C3=C(C)N(C4=CC=C(C)C=C4)N=N3)=C1)N
Biological Activity: hCAXII-IN-10 (Compound 18b) is a dual inhibitor of human carbonic anhydrase isoform XII (hCAXII) and cathepsin B, with a Ki value of 2.2 nM. hCAXII-IN-10 can inhibit the role of hCAXII in providing tumors with a pH microenvironment conducive to tumor growth, and is expected to be used in the study of tumor diseases[1].
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hCAXII-IN-10 | hCAXII-IN-10 (Compound 18b) is a dual inhibitor of human carbonic anhydrase isoform XII (hCAXII) and cathepsin B, with a Ki value of 2.2 nM. hCAXII-IN-10 can inhibit the role of hCAXII in providing tumors with a pH microenvironment conducive to tumor growth, and is expected to be used in the study of tumor diseases. | |||||||||||||||||||||
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References
Keywords
