hCAXII-IN-10
hCAXII-IN-10 (Compound 18b) is a dual inhibitor of human carbonic anhydrase isoform XII (hCAXII) and cathepsin B, with a Ki value of 2.2 nM. hCAXII-IN-10 can inhibit the role of hCAXII in providing tumors with a pH microenvironment conducive to tumor growth, and is expected to be used in the study of tumor diseases.
For research use only. We do not sell to patients.
- CAS No.: 3047757-68-3
- Formula: C20H19N7O3S
- Molecular Weight:437.47
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
hCAXII, cathepsin B[1].
Chemical Information
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CAS No. 3047757-68-3
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Molecular Weight 437.47
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Formula C20H19N7O3S
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SMILES
O=C(C1=NN(C2=CC=C(S(=O)(N)=O)C=C2)C(C3=C(C)N(C4=CC=C(C)C=C4)N=N3)=C1)N
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)