3048422-07-4
3048422-07-4
Chemical Structure
Antitumor agent-130
- CAS No.: 3048422-07-4
- Formula:C20H18ClNO5
- Molecular Weight:387.81
InChIKey: ZSDRRQBTAAIWJR-UHFFFAOYSA-M
SMILES: COC1=C(OC)C=C(C=C(C2=CC(OCO3)=C3C=C2OCC4)[N+]4=C5)C5=C1.[Cl-]
Biological Activity: Antitumor agent-130 (Compound 7b) is a p300 histone acetyltransferases (HAT) inhibitor with an IC50 of 1.51 μM. Antitumor agent-130 combinates with doxorubicin (HY-15142A) can significantly inhibit tumor growth and invasion in vitro and in vivo[1].
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Antitumor agent-130 | Antitumor agent-130 (Compound 7b) is a p300 histone acetyltransferases (HAT) inhibitor with an IC50 of 1.51 μM. Antitumor agent-130 combinates with doxorubicin (HY-15142A) can significantly inhibit tumor growth and invasion in vitro and in vivo. | |||||||||||||||||||||
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