3049802-45-8

PROTAC ALK degrader-1 Chemical Structure
3049802-45-8

Chemical Structure

PROTAC ALK degrader-1

  • CAS No.: 3049802-45-8
  • Formula:C47H55ClN10O9S
  • Molecular Weight:971.52

InChIKey: AQSXITZTNPSWAK-UHFFFAOYSA-N

SMILES: CC(C)S(C1=C(NC2=C(Cl)C=NC(NC3=C(OC(C)C)C=C(C4CCN(CC(NCC(NCCNC5=CC=CC(C(N6C7CCC(NC7=O)=O)=O)=C5C6=O)=O)=O)CC4)C(C)=C3)=N2)C=CC=C1)(=O)=O

Biological Activity: PROTAC ALK degrader-1 (compound B1) is an ALK degrader based on PROTACs, with the DC50 of 26 nM in H3122 EML4-ALK. PROTAC ALK degrader-1 can be used to synthesis PROTAC ALK degrader-2 (HY-161750) with superior bioavailability[1].

Cat. No. Product Name Purity Description Pricing
HY-161749 		PROTAC ALK degrader-1 PROTAC ALK degrader-1 (compound B1) is an ALK degrader based on PROTACs, with the DC50 of 26 nM in H3122 EML4-ALK. PROTAC ALK degrader-1 can be used to synthesis PROTAC ALK degrader-2 (HY-161750) with superior bioavailability.
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