3050872-76-6
3050872-76-6
Chemical Structure
MS8847N1
- CAS. Nr.: 3050872-76-6
- Formula:C72H102N10O8S
- Molecular Weight:1267.71
InChIKey: XBKIUDUZTGHUKY-ABRLEHMRSA-N
SMILES: CCN(C1CCOCC1)C2=CC(C3=CC=C(C=C3)CN4CCN(CC4)CCC(NCCCCCCCCCCC(N[C@@H](C(C)(C)C)C(N5[C@@H](C[C@H](C5)O)C(NCC6=CC=C(C7=C(N=CS7)C)C=C6)=O)=O)=O)=O)=CC(C(N(C)CC8=C(C)C=C(C)N(C)C8=O)=O)=C2C
Biological Activity: MS8847N1 is a negative control analog of MS8847 (HY-162250), which abolishes binding to EZH2 while retaining the activity of recruiting VHL. MS8847N1 does not induce EZH2 degradation. MS8847N1 can be used in PROTAC-related research[1].
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MS8847N1 | MS8847N1 is a negative control analog of MS8847 (HY-162250), which abolishes binding to EZH2 while retaining the activity of recruiting VHL. MS8847N1 does not induce EZH2 degradation. MS8847N1 can be used in PROTAC-related research. | |||||||||||||||||||||
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