3051852-76-4
3051852-76-4
Chemical Structure
BRD4-IN-10
- CAS No.: 3051852-76-4
- Formula:C24H30N8O3
- Molecular Weight:478.55
InChIKey: GFUQFCSWXXKACS-OAHLLOKOSA-N
SMILES: O=C1NC(C2(CCN(C3=NC(NC4=CC(N(C(C)C)[C@H](C)C(N5C)=O)=C5C=C4)=NC=C3)CC2)N1)=O
Biological Activity: BRD4-IN-10 (Compound 31) is a selective BRD4 inhibitor with an IC50 of 13.5 nM. BRD4-IN-10 can exert anti-inflammatory and anti-fibrotic effects. BRD4-IN-10 also has good metabolic stability, pharmacokinetic properties and safety. BRD4-IN-10 can be used in the research of renal fibrosis diseases[1].
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BRD4-IN-10 | BRD4-IN-10 (Compound 31) is a selective BRD4 inhibitor with an IC50 of 13.5 nM. BRD4-IN-10 can exert anti-inflammatory and anti-fibrotic effects. BRD4-IN-10 also has good metabolic stability, pharmacokinetic properties and safety. BRD4-IN-10 can be used in the research of renal fibrosis diseases. | |||||||||||||||||||||
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