305335-31-3
305335-31-3
Chemical Structure
MLN-4760
- CAS No.: 305335-31-3
- Formula:C19H23Cl2N3O4
- Molecular Weight:428.31
IUPAC Name: ((S)-1-carboxy-2-(1-(3,5-dichlorobenzyl)-1H-imidazol-5-yl)ethyl)-L-leucine
InChIKey: NTCCRGGIJNDEAB-IRXDYDNUSA-N
SMILES: O=C(O)[C@H](CC1=CN=CN1CC2=CC(Cl)=CC(Cl)=C2)N[C@H](C(O)=O)CC(C)C
Biological Activity: MLN-4760 is a potent and selective human ACE2 inhibitor (IC50, 0.44 nM), with excellent selectivity (>5000-fold) versus related enzymes including human testicular ACE (IC50, >100 μM) and bovine carboxypeptidase A (CPDA; IC50, 27 μM).
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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MLN-4760 | 99.78% | MLN-4760 is a potent and selective human ACE2 inhibitor (IC50, 0.44 nM), with excellent selectivity (>5000-fold) versus related enzymes including human testicular ACE (IC50, >100 μM) and bovine carboxypeptidase A (CPDA; IC50, 27 μM). | ||||||||||||||||||||
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