3063893-60-4
3063893-60-4
Chemical Structure
PLK1/BRD4-IN-5
- CAS No.: 3063893-60-4
- Formula:C31H44N8O3
- Molecular Weight:576.73
InChIKey: LBAXGISUFHVKPW-JXALWOEJSA-N
SMILES: CC[C@@H]1C(N(C2=CN=C(N=C2N1C3CCCC3)NC4=C(C=C5C(CCN5C(CN6C[C@@H](N[C@@H](C6)C)C)=O)=C4)OC)C)=O
Biological Activity: PLK1/BRD4-IN-5 (Compound SC10) is an orally active PLK1 and BRD4 inhibitor with IC50 values of 0.3 nM and 60.8 nM, respectively. PLK1/BRD4-IN-5 can induce MV4-11 cell block in S phase and apoptosis) in a dose-dependent manner. PLK1/BRD4-IN-5 can be used in cancer research[1].
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PLK1/BRD4-IN-5 | 98.80% | PLK1/BRD4-IN-5 (Compound SC10) is an orally active PLK1 and BRD4 inhibitor with IC50 values of 0.3 nM and 60.8 nM, respectively. PLK1/BRD4-IN-5 can induce MV4-11 cell block in S phase and apoptosis) in a dose-dependent manner. PLK1/BRD4-IN-5 can be used in cancer research. | ||||||||||||||||||||
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References
Keywords
