3069417-18-8
Chemical Structure
N-Sterol
- CAS No.: 3069417-18-8
- Formula:C34H57NO3
- Molecular Weight:527.82
InChIKey: UUWZGCKMDOULLI-LDVQOAMASA-N
SMILES: O=C(/C=C/N(CCOC)C)O[C@H]1CC[C@@]2([C@]3(CC[C@@]4([C@]([H])(CC[C@]4([C@@]3(CC=C2C1)[H])[H])[C@@H](CCCC(C)C)C)C)[H])C
Biological Activity: N-Sterol is a sterol lipid that has been used to generate lipid nanoparticles (LNPs) for delivery of mRNA in vitro and in vivo. N-Sterol LNPs are taken up in J774A.1 macrophages in a lipid composition-dependent manner via clathrin caveolae, caveolin-mediated endocytosis, micropinocytosis, or phagocytosis at different frequencies[1].
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N-Sterol | N-Sterol is a sterol lipid that has been used to generate lipid nanoparticles (LNPs) for delivery of mRNA in vitro and in vivo. N-Sterol LNPs are taken up in J774A.1 macrophages in a lipid composition-dependent manner via clathrin caveolae, caveolin-mediated endocytosis, micropinocytosis, or phagocytosis at different frequencies. | |||||||||||||||||||||
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Keywords
