3077847-90-3
3077847-90-3
Chemical Structure
AKT1-IN-10
- CAS No.: 3077847-90-3
- Formula:C31H29N7O3
- Molecular Weight:547.61
IUPAC Name: (1r,4r)-4-((5-(2-(2-aminopyridin-3-yl)-5-phenyl-3H-imidazo[4,5-b]pyridin-3-yl)-6-methylpyridin-2-yl)carbamoyl)cyclohexane-1-carboxylic acid
InChIKey: FQZSYYULAKXQMU-MEMLXQNLSA-N
SMILES: CC1=C(C=CC(NC([C@@H]2CC[C@H](CC2)C(O)=O)=O)=N1)N3C4=NC(C5=CC=CC=C5)=CC=C4N=C3C6=C(N=CC=C6)N
Biological Activity: AKT1-IN-10 (Compound I-118) is a non-covalent allosteric AKT1 inhibitor with an IC50 of < 500 μM. AKT1-IN-10 has oral bioavailability.AKT1-IN-10 can be used in cancer[1].
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AKT1-IN-10 | AKT1-IN-10 (Compound I-118) is a non-covalent allosteric AKT1 inhibitor with an IC50 of < 500 μM. AKT1-IN-10 has oral bioavailability.AKT1-IN-10 can be used in cancer. | |||||||||||||||||||||
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References
Keywords
