3081180-48-2
3081180-48-2
Chemical Structure
PROTAC BRD9 Degrader-8
- CAS No.: 3081180-48-2
- Formula:C46H49N5O6
- Molecular Weight:767.91
InChIKey: SVKZUEZCCKLNIM-UHFFFAOYSA-N
SMILES: O=C1C2=C(C(C3=CC(OC)=C(C(OC)=C3)CN4CCC(CN5CCC(CC5)C6=C7C(C8=CC=C7)=C(C=C6)N(C9C(NC(CC9)=O)=O)C8=O)CC4)=CN1C)C=CC=C2
Biological Activity: PROTAC BRD9 Degrader-8 is a selective, orally active BRD9 PROTAC degrader with a DC50 of 16 pM.\nPROTAC BRD9 Degrader-8 induces cell cycle arrest at the G1 phase and promotes apoptosis. PROTAC BRD9 Degrader-8 can be used for research on acute myeloid leukemia and diffuse large B-cell lymphoma[1].
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PROTAC BRD9 Degrader-8 | PROTAC BRD9 Degrader-8 is a selective, orally active BRD9 PROTAC degrader with a DC50 of 16 pM.\nPROTAC BRD9 Degrader-8 induces cell cycle arrest at the G1 phase and promotes apoptosis. PROTAC BRD9 Degrader-8 can be used for research on acute myeloid leukemia and diffuse large B-cell lymphoma. | |||||||||||||||||||||
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References
Keywords
