3083422-10-7
3083422-10-7
Chemical Structure
PROTAC PIN1 degrader-2
- CAS No.: 3083422-10-7
- Formula:C28H34ClN3O10S
- Molecular Weight:640.10
InChIKey: IOUIAMTYTPIQNP-UHFFFAOYSA-N
SMILES: O=C(CCCOC1=CC=CC(C(N2C3C(NC(CC3)=O)=O)=O)=C1C2=O)OCC(C)(CN(C4CCS(=O)(C4)=O)C(CCl)=O)C
Biological Activity: PROTAC PIN1 degrader-2 is a PROTAC PIN1 degrader. PROTAC PIN1 degrader-2 reduces PIN1-mediated oncogene expression, upregulates PIN1-inhibited tumor suppressor genes, and exerts killing effects on cancer cells. PROTAC PIN1 degrader-2 inhibits tumor growth in breast cancer mouse xenograft models. PROTAC PIN1 degrader-2 can be used for the research of breast cancer[1].
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PROTAC PIN1 degrader-2 | PROTAC PIN1 degrader-2 is a PROTAC PIN1 degrader. PROTAC PIN1 degrader-2 reduces PIN1-mediated oncogene expression, upregulates PIN1-inhibited tumor suppressor genes, and exerts killing effects on cancer cells. PROTAC PIN1 degrader-2 inhibits tumor growth in breast cancer mouse xenograft models. PROTAC PIN1 degrader-2 can be used for the research of breast cancer. | |||||||||||||||||||||
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