3083908-05-5
3083908-05-5
Chemical Structure
CXCR4-IN-3
- CAS No.: 3083908-05-5
- Formula:C20H25N3O2
- Molecular Weight:339.43
InChIKey: KVMLSNMTOXSTIK-UHFFFAOYSA-N
SMILES: O=C(C1=CC=CO1)N2CCN(C3CCN(C4=CC=CC=C4)CC3)CC2
Biological Activity: CXCR4-IN-3 (compound XVI) is an orally active and potent inhibitor targeting the inflammation-related receptor CXCR4, with an IC50 of 3.2 nM. CXCR4-IN-3 exhibits potent antichemotactic activity, at 79.19±2.33% inhibition. CXCR4-IN-3 shows anti-inflammatory activity. CXCR4-IN-3 can be used for IBD (inflammatory bowel disease) research[1].
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CXCR4-IN-3 | 99.69% | CXCR4-IN-3 (compound XVI) is an orally active and potent inhibitor targeting the inflammation-related receptor CXCR4, with an IC50 of 3.2 nM. CXCR4-IN-3 exhibits potent antichemotactic activity, at 79.19±2.33% inhibition. CXCR4-IN-3 shows anti-inflammatory activity. CXCR4-IN-3 can be used for IBD (inflammatory bowel disease) research. | ||||||||||||||||||||
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