3090685-34-7
3090685-34-7
Chemical Structure
WEE1 degrader 1
- CAS No.: 3090685-34-7
- Formula:C30H31N5O3
- Molecular Weight:509.60
InChIKey: BDZWATYRORWZMU-UBACFZPFSA-N
SMILES: O=C1N(C2CCC(NC2=O)=O)CC3=C1C=CC(C4=C(N[C@@]56CC(CC(C6)C7)CC7C5)N8C(C=CC=C8)=N4)=C3
Biological Activity: WEE1 degrader 1 (Compound 10) is a CRBN-dependent molecular glue degrader of WEE1 and casein kinase 1α (CK1α) with sub-2 nM DC50 values for both targets. WEE1 degrader 1 can be used for the research of acute lymphoblastic leukemia, acute monocytic leukemia, acute promyelocytic leukemia, colorectal adenocarcinoma, diffuse large b cell lymphoma[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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WEE1 degrader 1 | 99.74% | WEE1 degrader 1 (Compound 10) is a CRBN-dependent molecular glue degrader of WEE1 and casein kinase 1α (CK1α) with sub-2 nM DC50 values for both targets. WEE1 degrader 1 can be used for the research of acute lymphoblastic leukemia, acute monocytic leukemia, acute promyelocytic leukemia, colorectal adenocarcinoma, diffuse large b cell lymphoma. | ||||||||||||||||||||
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