3092219-09-2
3092219-09-2
Chemical Structure
YX862
- CAS No.: 3092219-09-2
- Formula:C48H72N8O5S
- Molecular Weight:873.20
InChIKey: ZOSWUNAJRAEGEW-YTIGDUPRSA-N
SMILES: O=C([C@@H](NC(CCCCCCCN1CCN(C2=CC=C(C=C2)C(NNCCCCCC)=O)CC1)=O)C(C)(C)C)N3[C@@H](C[C@H](C3)O)C(N[C@H](C4=CC=C(C=C4)C5=C(N=CS5)C)C)=O
Biological Activity: YX862 is a selective HDAC8 PROTAC degrader and induces the degradation of HDAC8 with maximum degradation ＞ 95% at 250 nM in MDA-MB-231 cells[1].
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YX862 | YX862 is a selective HDAC8 PROTAC degrader and induces the degradation of HDAC8 with maximum degradation ＞ 95% at 250 nM in MDA-MB-231 cells. | |||||||||||||||||||||
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References
Keywords
