3093642-22-6
3093642-22-6
Chemical Structure
PROTAC EZH2 Degrader-16
- CAS No.: 3093642-22-6
- Formula:C60H75N11O12
- Molecular Weight:1142.30
InChIKey: GJVQQTFVRDMDSG-UHFFFAOYSA-N
SMILES: CCN(C1=CC(C2=CC=C(CN3CCN(C(C4=CN(N=N4)CCOCCOCCOCCOCCNC5=C6C(C(N(C6=O)C7CCC(NC7=O)=O)=O)=CC=C5)=O)CC3)C=C2)=CC(C(NCC8=C(C)C=C(C)NC8=O)=O)=C1C)C9CCOCC9
Biological Activity: PROTAC EZH2 Degrader-16 (compound 51) is a PROTAC protein degrader targeting EZH2 with an IC50 of 13.74 μM in SU-DHL-6 cells. PROTAC EZH2 Degrader-16 exerts antiproliferative activity against diffuse large B-cell lymphoma cells. PROTAC EZH2 Degrader-16 can be used for the research of diffuse large B-cell lymphoma[1].
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PROTAC EZH2 Degrader-16 | PROTAC EZH2 Degrader-16 (compound 51) is a PROTAC protein degrader targeting EZH2 with an IC50 of 13.74 μM in SU-DHL-6 cells. PROTAC EZH2 Degrader-16 exerts antiproliferative activity against diffuse large B-cell lymphoma cells. PROTAC EZH2 Degrader-16 can be used for the research of diffuse large B-cell lymphoma. | |||||||||||||||||||||
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