3093642-36-2
Chemical Structure
PROTAC EZH2 Degrader-21
- CAS No.: 3093642-36-2
- Formula:C60H80N10O9
- Molecular Weight:1085.34
InChIKey: MOPHLHXJMOQYMH-BIOIQHPWSA-N
SMILES: CCN(C1CCOCC1)C2=CC(C3=CC=C(C=C3)CN4CCN(CC4)C(CCC5=CN(N=N5)CCCC(N[C@@H]([C@H](O)C(N[C@@H](CC(C)C)C(OC)=O)=O)CC6=CC=CC=C6)=O)=O)=CC(C(NCC7=C(C=C(NC7=O)C)C)=O)=C2C
Biological Activity: PROTAC EZH2 Degrader-21 is an EZH2 degrader developed based on PROTAC technology. PROTAC EZH2 Degrader-21 induces the degradation of the target protein EZH2 via specific recruitment of the cIAP E3 ligase. PROTAC EZH2 Degrader-21 exhibits significant inhibitory activity in a variety of lymphoma cell lines. PROTAC EZH2 Degrader-21 can be used for research on the pathogenesis of lymphoma[1].
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PROTAC EZH2 Degrader-21 | PROTAC EZH2 Degrader-21 is an EZH2 degrader developed based on PROTAC technology. PROTAC EZH2 Degrader-21 induces the degradation of the target protein EZH2 via specific recruitment of the cIAP E3 ligase. PROTAC EZH2 Degrader-21 exhibits significant inhibitory activity in a variety of lymphoma cell lines. PROTAC EZH2 Degrader-21 can be used for research on the pathogenesis of lymphoma. | |||||||||||||||||||||
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