PROTAC EZH2 Degrader-21
PROTAC EZH2 Degrader-21 is an EZH2 degrader developed based on PROTAC technology. PROTAC EZH2 Degrader-21 induces the degradation of the target protein EZH2 via specific recruitment of the cIAP E3 ligase. PROTAC EZH2 Degrader-21 exhibits significant inhibitory activity in a variety of lymphoma cell lines. PROTAC EZH2 Degrader-21 can be used for research on the pathogenesis of lymphoma.
(Pink: EZH2 ligand (HY-147230); Blue: cIAP ligand (HY-137159); Black: linker).
For research use only. We do not sell to patients.
- CAS No.: 3093642-36-2
- Formula: C60H80N10O9
- Molecular Weight:1085.34
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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EZH2 |
cIAP |
Chemical Information
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CAS No. 3093642-36-2
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Molecular Weight 1085.34
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Formula C60H80N10O9
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SMILES
CCN(C1CCOCC1)C2=CC(C3=CC=C(C=C3)CN4CCN(CC4)C(CCC5=CN(N=N5)CCCC(N[C@@H]([C@H](O)C(N[C@@H](CC(C)C)C(OC)=O)=O)CC6=CC=CC=C6)=O)=O)=CC(C(NCC7=C(C=C(NC7=O)C)C)=O)=C2C
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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