3097367-11-5
Chemical Structure
HV1-IN-2
- CAS No.: 3097367-11-5
- Formula:C17H14F3N3O
- Molecular Weight:333.31
IUPAC Name: 5-(4-((3-(trifluoromethyl)benzyl)oxy)phenyl)-1H-imidazol-2-amine
InChIKey: YWGGKUTYSQUPDU-UHFFFAOYSA-N
SMILES: NC1=NC=C(C2=CC=C(OCC3=CC=CC(C(F)(F)F)=C3)C=C2)N1
Biological Activity: HV1-IN-2 (Compound 14c) is a human voltage-gated proton channel (HV1) inhibitor with an IC50 of 2.14 μM. HV1-IN-2 has a potent anticancer activity with significant antiproliferative effects against THP-1 and MCF-7 cells. HV1-IN-2 can be used for cancers research, such as colorectal tumours, leukaemia, and breast cancer[1].
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HV1-IN-2 | 99.31% | HV1-IN-2 (Compound 14c) is a human voltage-gated proton channel (HV1) inhibitor with an IC50 of 2.14 μM. HV1-IN-2 has a potent anticancer activity with significant antiproliferative effects against THP-1 and MCF-7 cells. HV1-IN-2 can be used for cancers research, such as colorectal tumours, leukaemia, and breast cancer. | ||||||||||||||||||||
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Keywords
