3099381-90-2
3099381-90-2
Chemical Structure
S34-1040
- CAS No.: 3099381-90-2
- Formula:C18H17N3O2
- Molecular Weight:307.35
InChIKey: GVMOTRRBBVEWMA-UHFFFAOYSA-N
SMILES: N#CC1=CC=C(C=C1)CN(C)C(C2=CC(C(C3CC3)=O)=CN2)=O
Biological Activity: S34-1040 is an AKR1C3 inhibitor with a human IC50 of 0.03 μM and exhibits no detectable inhibition of AKR1C1, AKR1C2, or AKR1C4. S34-1040 functions as a chemosensitizer and restores sensitivity of doxorubicin-resistant breast cancer cells to doxorubicin. S34-1040 can be used for the research of doxorubicin-resistant breast cancer[1].
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S34-1040 | S34-1040 is an AKR1C3 inhibitor with a human IC50 of 0.03 μM and exhibits no detectable inhibition of AKR1C1, AKR1C2, or AKR1C4. S34-1040 functions as a chemosensitizer and restores sensitivity of doxorubicin-resistant breast cancer cells to doxorubicin. S34-1040 can be used for the research of doxorubicin-resistant breast cancer. | |||||||||||||||||||||
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