310392-94-0
310392-94-0
Chemical Structure
Wf-516
- CAS No.: 310392-94-0
- Formula:C25H25Cl2N3O4
- Molecular Weight:502.39
IUPAC Name: (S)-1-(4-(3,4-dichlorophenyl)piperidin-1-yl)-3-((2-(5-methyl-1,3,4-oxadiazol-2-yl)benzofuran-4-yl)oxy)propan-2-ol
InChIKey: XIYDIPLATGRHEC-SFHVURJKSA-N
SMILES: O[C@H](COC1=C2C=C(C3=NN=C(C)O3)OC2=CC=C1)CN(CC4)CCC4C5=CC=C(Cl)C(Cl)=C5
Biological Activity: Wf-516 is an inhibitor of 5-HT reuptake, and an antagonist of 5-HT1A and 5-HT2A receptors, with Ki of 5 nM and 40 nM for 5-HT1A receptor and 5-HT2A receptor in humans, respectively, and has potent antidepressant activity.
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Wf-516 | Wf-516 is an inhibitor of 5-HT reuptake, and an antagonist of 5-HT1A and 5-HT2A receptors, with Ki of 5 nM and 40 nM for 5-HT1A receptor and 5-HT2A receptor in humans, respectively, and has potent antidepressant activity. | |||||||||||||||||||||
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Keywords
