3122151-07-6
3122151-07-6
Chemical Structure
YAP-TEAD-IN-4
- CAS No.: 3122151-07-6
- Formula:C21H22N2O4S2
- Molecular Weight:430.54
InChIKey: XPZABBIRJGJFQV-UHFFFAOYSA-N
SMILES: CC(C=C1)=CC2=C1N3C4=C2CCCC4N(S(C5=C(C(OC)=O)SC=C5)(=O)=O)CC3
Biological Activity: YAP-TEAD-IN-4 is a YAP-TEAD protein-protein interaction inhibitor. YAP-TEAD-IN-4 inhibits YAP-TEAD protein-protein interaction and suppresses TEAD-dependent transcriptional activity, with an IC50 of 1.19 μM. YAP-TEAD-IN-4 reduces lung tumor burden and lung colonization in the B16-F10 melanoma lung colonization mouse model. YAP-TEAD-IN-4 can be used for melanoma-related research[1].
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YAP-TEAD-IN-4 | YAP-TEAD-IN-4 is a YAP-TEAD protein-protein interaction inhibitor. YAP-TEAD-IN-4 inhibits YAP-TEAD protein-protein interaction and suppresses TEAD-dependent transcriptional activity, with an IC50 of 1.19 μM. YAP-TEAD-IN-4 reduces lung tumor burden and lung colonization in the B16-F10 melanoma lung colonization mouse model. YAP-TEAD-IN-4 can be used for melanoma-related research. | |||||||||||||||||||||
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