3127025-65-1
Chemical Structure
Anticancer agent 330
- CAS No.: 3127025-65-1
- Formula:C63H87BrN3O10P
- Molecular Weight:1157.26
InChIKey: BODFAEUUTGFVMK-LGRPOBNKSA-N
SMILES: [H][C@]1(O[C@H](CC[C@@H]1C)[C@H](C(O)=O)CC)[C@H]([C@@H]([C@@H](C([C@@H]([C@H]2O[C@@]3([C@@H](C[C@@H]2C)C)C=CC([C@@]4(O3)CC[C@@]([C@H]5CC[C@](CC)([C@@H](O5)C)O)(O4)C)N6C=C(N=N6)C[P+](C7=CC=CC=C7)(C8=CC=CC=C8)C9=CC=CC=C9)CC)=O)C)O)C.[Br-]
Biological Activity: Anticancer agent 330 is a semi-synthetic derivative of Salinomycin (HY-15597) conjugated with triphenylphosphine, as well as an anticancer agent. Anticancer agent 330 induces G0/G1 phase cell cycle arrest. Anticancer agent 330 reduces the production of ROS in cells. Anticancer agent 330 impairs mitochondrial integrity. Anticancer agent 330 promotes Autophagy. Anticancer agent 330 can be used in research related to ovarian cancer[1].
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Anticancer agent 330 | Anticancer agent 330 is a semi-synthetic derivative of Salinomycin (HY-15597) conjugated with triphenylphosphine, as well as an anticancer agent. Anticancer agent 330 induces G0/G1 phase cell cycle arrest. Anticancer agent 330 reduces the production of ROS in cells. Anticancer agent 330 impairs mitochondrial integrity. Anticancer agent 330 promotes Autophagy. Anticancer agent 330 can be used in research related to ovarian cancer. | |||||||||||||||||||||
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Keywords