3129164-13-9
3129164-13-9
Chemical Structure
URAT1-IN-17
- CAS No.: 3129164-13-9
- Formula:C20H16BrN3O2S
- Molecular Weight:442.33
InChIKey: LNYUDDIXNZDIPM-UHFFFAOYSA-N
SMILES: OC(C(SC1=NC=NC2=C1N(C=C2)CC3=CC=C(C4=C3C=CC=C4)Br)C)=O
Biological Activity: URAT1-IN-17 is an orally active URAT1 inhibitor with an IC50 of 5.32 μM in HEK293T cells. URAT1-IN-17 inhibits URAT1-mediated uric acid reabsorption in the renal proximal tubule, thereby reducing serum uric acid levels. URAT1-IN-17 weakly inhibits OAT1-mediated organic anion transport. URAT1-IN-17 can be used for research on hyperuricemia[1].
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URAT1-IN-17 | URAT1-IN-17 is an orally active URAT1 inhibitor with an IC50 of 5.32 μM in HEK293T cells. URAT1-IN-17 inhibits URAT1-mediated uric acid reabsorption in the renal proximal tubule, thereby reducing serum uric acid levels. URAT1-IN-17 weakly inhibits OAT1-mediated organic anion transport. URAT1-IN-17 can be used for research on hyperuricemia. | |||||||||||||||||||||
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