3131794-81-2
3131794-81-2
Chemical Structure
BChE-IN-51
- CAS. Nr.: 3131794-81-2
- Formula:C26H25FN4O
- Molecular Weight:428.50
InChIKey: YYTNLRGJPHXWEF-UHFFFAOYSA-N
SMILES: FC1=CC=CC=C1C(N/C(NC2=CC=CC=C2CC)=N/CCC3=CNC4=C3C=CC=C4)=O
Biological Activity: BChE-IN-51 is a selective, blood-brain barrier-permeable, orally active BChE inhibitor with an IC50 of 0.03 μM against hBChE. BChE-IN-51 reduces ROS production, protects neurons from the toxic effects of hydrogen peroxide and Aβ1-42, and alleviates cognitive impairment. BChE-IN-51 can be used for the research of Alzheimer's disease[1].
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BChE-IN-51 | BChE-IN-51 is a selective, blood-brain barrier-permeable, orally active BChE inhibitor with an IC50 of 0.03 μM against hBChE. BChE-IN-51 reduces ROS production, protects neurons from the toxic effects of hydrogen peroxide and Aβ1-42, and alleviates cognitive impairment. BChE-IN-51 can be used for the research of Alzheimer's disease. | |||||||||||||||||||||
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References
Keywords
