3137885-65-2
3137885-65-2
Chemical Structure
PROTAC IRF5 degrader-3
- CAS No.: 3137885-65-2
- Formula:C48H53F4N9O4
- Molecular Weight:895.99
InChIKey: ADDBKJAYOBHSFA-QSDNSWBISA-N
SMILES: CN1C2=CC(C3C(F)(CN([C@@H]4CC[C@@H](C5=CC(OC6=C7C(N(C(N7)=O)C)=CC=C6)=NC(C8=CN(C=N8)[C@H](C9CCC(F)(CC9)F)C)=C5)CC4)CC3)F)=CC=C2C(C%10C(NC(CC%10)=O)=O)=N1
Biological Activity: PROTAC IRF5 degrader-3 is a PROTAC degrader targeting interferon regulatory factor 5 (IRF5), with a DC50 of 1-10 nM. PROTAC IRF5 degrader-3 can be used in research on IRF5-associated autoimmune and inflammatory diseases, such as systemic lupus erythematosus and rheumatoid arthritis[1].
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PROTAC IRF5 degrader-3 | PROTAC IRF5 degrader-3 is a PROTAC degrader targeting interferon regulatory factor 5 (IRF5), with a DC50 of 1-10 nM. PROTAC IRF5 degrader-3 can be used in research on IRF5-associated autoimmune and inflammatory diseases, such as systemic lupus erythematosus and rheumatoid arthritis. | |||||||||||||||||||||
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