314039-40-2
314039-40-2
Chemical Structure
CD38-IN-5
- CAS No.: 314039-40-2
- Formula:C18H23N5
- Molecular Weight:309.41
InChIKey: NXZXRPKKYIPBNO-UHFFFAOYSA-N
SMILES: CC1=CC(C)=CC2=C(C)N=C(N=C21)NC3=NC(C)=CC(C)(C)N3
Biological Activity: CD38-IN-5 (compound 1) is a CD38 inhibitor that selectively inhibits CD38 hydrolase with an IC50 of 4.0 μM. CD38-IN-5 does not inhibits CD38 cyclase. CD38-IN-5 is highly effective at promoting NK cell-mediated tumor toxicity. CD38-IN-5 increases NADH+ and IFNγ levels in activated PBMCs. CD38-IN-5 can be used for the study of cancer[1].
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CD38-IN-5 | CD38-IN-5 (compound 1) is a CD38 inhibitor that selectively inhibits CD38 hydrolase with an IC50 of 4.0 μM. CD38-IN-5 does not inhibits CD38 cyclase. CD38-IN-5 is highly effective at promoting NK cell-mediated tumor toxicity. CD38-IN-5 increases NADH+ and IFNγ levels in activated PBMCs. CD38-IN-5 can be used for the study of cancer. | |||||||||||||||||||||
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References
Keywords
