331257-53-5
Chemical Structure
Aprinocarsen sodium
Synonym(s): ISIS 3521 sodium
- CAS No.: 331257-53-5
- Formula:C196H230N68Na19O105P19S19
- Molecular Weight:6435.2 (free acid)
IUPAC Name: (2Z,4E)-5-((1S,6S)-1-hydroxy-2-(hydroxymethyl)-6-methyl-6-(methyl-d3)-4-oxocyclohex-2-en-1-yl)-3-methylpenta-2,4-dienoic-5-d acid
SMILES: [Aprinocarsen (sodium)]
Biological Activity: Aprinocarsen (ISIS 3521) sodium, a specific antisense oligonucleotide inhibitor of protein kinase C-alpha (PKC-α). Aprinocarsen sodium is a 20-mer oligonucleotide, it regulates cell differentiation and proliferation. Aprinocarsen sodium inhibits the growth of human tumor cell lines in nude mice. Aprinocarsen sodium shows the value as a chemotherapeutic compound of human cancers[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
Aprinocarsen sodium | 98.42% | Aprinocarsen (ISIS 3521) sodium, a specific antisense oligonucleotide inhibitor of protein kinase C-alpha (PKC-α). Aprinocarsen sodium is a 20-mer oligonucleotide, it regulates cell differentiation and proliferation. Aprinocarsen sodium inhibits the growth of human tumor cell lines in nude mice. Aprinocarsen sodium shows the value as a chemotherapeutic compound of human cancers. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
Keywords
