332926-04-2

PF-00277343 Chemical Structure
332926-04-2

Chemical Structure

PF-00277343

  • CAS No.: 332926-04-2
  • Formula:C24H20FN3O4
  • Molecular Weight:433.43

IUPAC Name: 2-(4-(3-(4-fluorobenzyl)-4-hydroxyphenoxy)-3,5-dimethylphenyl)-1,2,4-triazine-3,5(2H,4H)-dione

InChIKey: HQXKNHQWCAXRDN-UHFFFAOYSA-N

SMILES: O=C(N(N=C1)C2=CC(C)=C(C(C)=C2)OC3=CC=C(C(CC4=CC=C(C=C4)F)=C3)O)NC1=O

Biological Activity: PF-00277343 is a selective and skin-penetrable THR-β (Ki: 0.51 nM for THR-β, 8.0 nM for THR-α) agonist. PF-00277343 is effective against androgenetic alopecia in animal models[1].

Cat. No. Product Name Purity Description Pricing
HY-118978 		PF-00277343 PF-00277343 is a selective and skin-penetrable THR-β (Ki: 0.51 nM for THR-β, 8.0 nM for THR-α) agonist. PF-00277343 is effective against androgenetic alopecia in animal models.
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