33458-93-4
33458-93-4
Chemical Structure
AH 6809
- No. CAS: 33458-93-4
- Formula:C17H14O5
- Molecular Weight:298.29
IUPAC Name: 6-isopropoxy-9-oxo-9H-xanthene-2-carboxylic acid
InChIKey: AQFFXPQJLZFABJ-UHFFFAOYSA-N
SMILES: O=C1C2=C(C=CC(C(O)=O)=C2)OC3=CC(OC(C)C)=CC=C31
Biological Activity: AH 6809 is an antagonist of EP and DP receptor, with Kis of 1217, 1150, 1597, and 1415 nM for the cloned human EP1, EP2, EP3-III, and DP receptor respectively. AH 6809 has a Ki of 350 nM for mouse EP2 receptor[1][2][3].
| Referencia número | Nombre del producto | Pureza | Descripciòn | Pricing | |||||||||||||||||||
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AH 6809 | 99.57% | AH 6809 is an antagonist of EP and DP receptor, with Kis of 1217, 1150, 1597, and 1415 nM for the cloned human EP1, EP2, EP3-III, and DP receptor respectively. AH 6809 has a Ki of 350 nM for mouse EP2 receptor. | ||||||||||||||||||||
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AH 6809 (Standard) | ≥98% | AH 6809 (Standard) is the analytical standard of AH 6809. This product is intended for research and analytical applications. AH 6809 is an antagonist of EP and DP receptor, with Kis of 1217, 1150, 1597, and 1415 nM for the cloned human EP1, EP2, EP3-III, and DP receptor respectively. AH 6809 has a Ki of 350 nM for mouse EP2 receptor. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.79
HY-121048AH 7725 -
Similarity Score 0.79
HY-W5869609-Oxo-9H-xanthene-2,6-dicarboxylic acid -
Similarity Score 0.77
HY-W5869619-Oxo-9H-xanthene-2,7-dicarboxylic acid -
Similarity Score 0.72
HY-W6653383,6-Dimethoxy-9H-xanthen-9-one -
Similarity Score 0.71
![Dibenzo[b,d]furan-2,8-dicarboxylic acid Chemical Structure](//file.medchemexpress.com/product_pic/hy-w1049911.gif)
HY-W1049911Dibenzo[b,d]furan-2,8-dicarboxylic acid -
Similarity Score 0.70
HY-159926Tixanox sodium -
Similarity Score 0.70
HY-174298Ipriflavone metabolites IV -
Similarity Score 0.70
HY-N138352,6-Dihydroxyxanthone -
Similarity Score 0.68
HY-N0094Ipriflavone -
Explore the MedChemAI to find more analogs
![Dibenzo[b,d]furan-2,8-dicarboxylic acid Chemical Structure](http://file.medchemexpress.com/product_pic/hy-w1049911.gif)
References
- [1]. Abramovitz M, et, al. The utilization of recombinant prostanoid receptors to determine the affinities and selectivities of prostaglandins and related analogs. Biochim Biophys Acta. 2000 Jan 17;1483(2):285-93. [Content Brief]
- [2]. Kiriyama M, et, al. Ligand binding specificities of the eight types and subtypes of the mouse prostanoid receptors expressed in Chinese hamster ovary cells. Br J Pharmacol. 1997 Sep;122(2):217-24. [Content Brief]
- [3]. Woodward DF, et, al. 6-Isopropoxy-9-oxoxanthene-2-carboxylic acid (AH 6809), a human EP2 receptor antagonist. Biochem Pharmacol. 1995 Nov 9;50(10):1731-3. [Content Brief]
