337536-53-5
Chemical Structure
8-Nitroguanosine
- CAS No.: 337536-53-5
- Formula:C10H12N6O7
- Molecular Weight:328.24
IUPAC Name: 2-amino-9-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-8-nitro-1,9-dihydro-6H-purin-6-one
InChIKey: KGUOMRFOXYDMAH-UMMCILCDSA-N
SMILES: O[C@H]1[C@@H](O)[C@H](N(C([N+]([O-])=O)=N2)C3=C2C(NC(N)=N3)=O)O[C@@H]1CO
Biological Activity: 8-Nitroguanosine is a guanosine analogue. Some guanosine analogs have immunostimulatory activity. In some animal models, they also induce type I interferons, producing antiviral effects. Studies have shown that the functional activity of guanosine analogs is dependent on the activation of Toll-like receptor 7 (TLR7)[1].
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8-Nitroguanosine | 95.52% | 8-Nitroguanosine is a guanosine analogue. Some guanosine analogs have immunostimulatory activity. In some animal models, they also induce type I interferons, producing antiviral effects. Studies have shown that the functional activity of guanosine analogs is dependent on the activation of Toll-like receptor 7 (TLR7). | ||||||||||||||||||||
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Keywords
