33823-18-6
Chemical Structure
8-MA-cAMP
Synonym(s): 8-Methylamino-cAMP
- CAS No.: 33823-18-6
- Formula:C11H15N6O6P
- Molecular Weight:358.25
IUPAC Name: (4aR,6R,7R,7aS)-6-(6-amino-8-(methylamino)-9H-purin-9-yl)-2,7-dihydroxytetrahydro-4H-furo[3,2-d][1,3,2]dioxaphosphinine 2-oxide
InChIKey: BSUDVADBEMYPCQ-KQYNXXCUSA-N
SMILES: O[C@@H]1[C@H](OP2(O)=O)[C@@H](CO2)O[C@H]1N3C(NC)=NC4=C3N=CN=C4N
Biological Activity: 8-MA-cAMP (8-Methylamino-cAMP) is a cyclic AMP analog that acts as a site-selective PKA agonist with similar affinity for the B site of type I and type II protein kinase A. 8-MA-cAMP is used in conjunction with priming analogs that show site A preference, such as 8-piperidinyl cAMP, to achieve selective stimulation of type I[1].
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8-MA-cAMP | 8-MA-cAMP (8-Methylamino-cAMP) is a cyclic AMP analog that acts as a site-selective PKA agonist with similar affinity for the B site of type I and type II protein kinase A. 8-MA-cAMP is used in conjunction with priming analogs that show site A preference, such as 8-piperidinyl cAMP, to achieve selective stimulation of type I. | |||||||||||||||||||||
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