34209-69-3
Chemical Structure
Trachelogenin
Synonym(s): (-)-Trachelogenin
- CAS. Nr.: 34209-69-3
- Formula:C21H24O7
- Molecular Weight:388.41
IUPAC Name: (3S,4S)-4-(3,4-dimethoxybenzyl)-3-hydroxy-3-(4-hydroxy-3-methoxybenzyl)dihydrofuran-2(3H)-one
InChIKey: YFVZKLQNMNKWSB-BTYIYWSLSA-N
SMILES: O[C@]1([C@H](COC1=O)CC(C=C2)=CC(OC)=C2OC)CC(C=C3)=CC(OC)=C3O
Biological Activity: Trachelogenin ((-)-Trachelogenin) is an HCV entry inhibitor without genotype specificity, and with low cytotoxicity. Trachelogenin inhibits HCVcc infection and HCVpp cell entry in a dose-dependent manner with an IC50 of 0.325 and 0.259 μg/mL in HCVcc and HCVpp models, respectively. Trachelogenin exhibits effective antiviral, anti-inflammatory and analgesic effects[1].
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Trachelogenin | 99.56% | Trachelogenin ((-)-Trachelogenin) is an HCV entry inhibitor without genotype specificity, and with low cytotoxicity. Trachelogenin inhibits HCVcc infection and HCVpp cell entry in a dose-dependent manner with an IC50 of 0.325 and 0.259 μg/mL in HCVcc and HCVpp models, respectively. Trachelogenin exhibits effective antiviral, anti-inflammatory and analgesic effects. | ||||||||||||||||||||
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Keywords
