3459-18-5
Chemical Structure
4-Nitrophenyl-N-acetyl-β-D-glucosaminide
- CAS No.: 3459-18-5
- Formula:C14H18N2O8
- Molecular Weight:342.30
IUPAC Name: N-((2S,3R,4R,5S,6R)-4,5-Dihydroxy-6-(hydroxymethyl)-2-(4-nitrophenoxy)tetrahydro-2H-pyran-3-yl)acetamide
InChIKey: OMRLTNCLYHKQCK-DHGKCCLASA-N
SMILES: CC(N[C@H]([C@H]([C@@H]([C@H](O1)CO)O)O)[C@@H]1OC2=CC=C(C=C2)[N+]([O-])=O)=O
Biological Activity: 4-Nitrophenyl-N-acetyl-β-D-glucosaminide, an artificial substrate of N-acetyl-beta-D-hexosaminidase (NAGase), can be used in rapid and accurate rate assay for N-acetyl-beta-D-hexosaminidase. 4-Nitrophenyl-N-acetyl-β-D-glucosaminide is highly soluble and stable. 4-Nitrophenyl-N-acetyl-β-D-glucosaminide can be used for the study of renal tubular injury[1][2][3].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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4-Nitrophenyl-N-acetyl-β-D-glucosaminide | 99.97% | 4-Nitrophenyl-N-acetyl-β-D-glucosaminide, an artificial substrate of N-acetyl-beta-D-hexosaminidase (NAGase), can be used in rapid and accurate rate assay for N-acetyl-beta-D-hexosaminidase. 4-Nitrophenyl-N-acetyl-β-D-glucosaminide is highly soluble and stable. 4-Nitrophenyl-N-acetyl-β-D-glucosaminide can be used for the study of renal tubular injury. | ||||||||||||||||||||
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References
- [1]. Shibata H, et, al. Rate assay of N-acetyl-beta-D-hexosaminidase with 4-nitrophenyl N-acetyl-beta-D-glucosaminide as an artificial substrate. Clin Chim Acta. 1996 Jul 15;251(1):53-64. [Content Brief]
- [2]. Skálová S, et al. The diagnostic role of urinary N-acetyl-beta-D-glucosaminidase (NAG) activity in the detection of renal tubular impairment. Acta Medica (Hradec Kralove). 2005;48(2):75-80. [Content Brief]
- [3]. Zou E, et al. Effects of hypoxia and sedimentary naphthalene on the activity of N-acetyl-beta-glucosaminidase in the epidermis of the brown shrimp, Penaeus aztecus. Bull Environ Contam Toxicol. 2009 May;82(5):579-82. [Content Brief]
