34622-39-4
34622-39-4
Chemical Structure
L-Pyrohomoglutamic acid
- CAS No.: 34622-39-4
- Formula:C6H9NO3
- Molecular Weight:143.14
IUPAC Name: (S)-6-oxopiperidine-2-carboxylic acid
InChIKey: FZXCPFJMYOQZCA-BYPYZUCNSA-N
SMILES: O=C([C@H](CCC1)NC1=O)O
Biological Activity: L-Pyrohomoglutamic acid is an amino acid building block. L-Pyrohomoglutamic acid can be used to synthesize ligands for FK506-binding proteins (FKBPs) and histone deacetylase (HDAC) inhibitors[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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L-Pyrohomoglutamic acid | 99.51% | L-Pyrohomoglutamic acid is an amino acid building block. L-Pyrohomoglutamic acid can be used to synthesize ligands for FK506-binding proteins (FKBPs) and histone deacetylase (HDAC) inhibitors. | ||||||||||||||||||||
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References
- [1]. Pomplun S, et al. Rational design and asymmetric synthesis of potent and neurotrophic ligands for FK506-binding proteins (FKBPs). Angew Chem Int Ed Engl. 2015 Jan 2;54(1):345-8. [Content Brief]
- [2]. Taddei M, et al. Lactam based 7-amino suberoylamide hydroxamic acids as potent HDAC inhibitors. Bioorg Med Chem Lett. 2014 Jan 1;24(1):61-4. [Content Brief]
Keywords
